Development of Chemistry-Based Screening Platform for Access to Mirror-Image Library of Natural Products

Development of Chemistry-Based Screening Platform for Access to Mirror-Image Library of Natural Products

Noguchi, Taro

Springer Verlag, Singapore

11/2017

80

Dura

Inglês

9789811066221

15 a 20 dias

This thesis mainly describes the development of a screening process for a mirror-image library of chiral natural products. It demonstrates how, by using mirror-image proteins for the screening of available natural products, unavailable mirror-image isomers of natural products can be screened in a mirror process.
Introduction.- Development of a Mirror-image Screening Process by Using Synthetic Proteins.- Synthesis of Grb2 SH2 Domain Proteins for Mirror-image Screening Systems.- Conclusions.
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